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D2531 Sigma-Aldrich

Dextromethorphan hydrobromide monohydrate

≥99% (TLC)

Synonym: (9S,13S,14S)-3-Methoxy-17-methylmorphinan hydrobromide, d-3-Methoxy-N-methylmorphinan hydrobromide monohydrate

  • CAS Number 6700-34-1

  • Empirical Formula (Hill Notation) C18H25NO · HBr · H2O

  • Molecular Weight 370.32

  •  Beilstein/REAXYS Number 6453793

  •  MDL number MFCD02173901

  •  PubChem Substance ID 57654086

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Description

Application

Dextromethorphan hydrobromide monohydrate has been used as a substrate for cytochrome P450 2D6 enzyme action, in potassium phosphate buffer for measuring P450 activity and is used in enzyme inhibition studies.

Packaging

5, 10, 50 g in poly bottle

Biochem/physiol Actions

Dextromethorphan hydrobromide is an allosteric antagonist at N-methyl D- aspartate (NMDA)-controlled ion channels and antagonist at voltage-dependent channels. Dextromethorphan hydrobromide is useful in treating dry cough.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Certificate of Origin

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Protocols & Articles
Peer-Reviewed Papers
15

References

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