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D5878 Sigma-Aldrich

Digitoxin

≥92% (HPLC), powder

Synonym: 5β,20(22)-Cardenolide-3β,14-diol-3-(O-2,6-dideoxy-β-D-ribo-hexopyranosyl-[1→4]-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-[1→4]-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy, Digitoxoside, Lanatoxin

  • CAS Number 71-63-6

  • Empirical Formula (Hill Notation) C41H64O13

  • Molecular Weight 764.94

  •  Beilstein/REAXYS Number 76678

  •  EC Number 200-760-5

  •  MDL number MFCD00003686

  •  PubChem Substance ID 24893976

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Description

General description

Digitoxin is a cardiac glycoside (CG). It is a cardiotonic drug, which exhibits cardiac and anti-cancer properties. Digitoxin inhibits nuclear factor kappa B (NF-κB) signaling. It is used to treat congestive heart failure and cardiac arrhythmia. Digitoxin prevents microtubule formation.

Application

Digitoxin has been used as a labeled drugs for binding sites on human serum albumin (HSA). It has also been used to test its anti-transmissible gastroenteritis virus (TGEV) activity.

Packaging

1, 5, 10 g in glass bottle

250, 500 mg in glass bottle

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 2811 6.1 / PGI
WGK Germany 
3
RTECS 
IH2275000

Documents

Certificate of Analysis

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Certificate of Origin

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Protocols & Articles
Peer-Reviewed Papers
15

References

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