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D7145 Sigma-Aldrich

2′-Deoxyguanosine monohydrate

99-100%

Synonym: 9-(2-Deoxy-β-D-ribofuranosyl)guanine, Guanine-2′-deoxyriboside

  • CAS Number 312693-72-4

  • Empirical Formula (Hill Notation) C10H13N5O4 · H2O

  • Molecular Weight 285.26

  •  Beilstein/REAXYS Number 39814

  •  MDL number MFCD00150760

  •  PubChem Substance ID 24894083

  •  NACRES NA.51

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Properties

Related Categories Biochemicals and Reagents, Nucleoside Analogs, Nucleosides, Nucleotides, Oligonucleotides More...
InChI Key   LZSCQUCOIRGCEJ-FPKZOZHISA-N
assay   99-100%

Description

Application

Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.

Packaging

1, 5 g in poly bottle

25, 100 mg in poly bottle

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

HPLC Analysis of Deoxyribonucleosides on Ascentis® Si

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Deoxyribonucleosides on Ascentis® Si
Keywords: Chromatography, High performance liquid chromatography

HPLC Analysis of Nucleosides on Ascentis® Phenyl

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Nucleosides on Ascentis® Phenyl
Keywords: Chromatography, High performance liquid chromatography

HPLC Analysis of Nucleosides on Ascentis® Si (HILIC Mode)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Nucleosides on Ascentis® Si (HILIC Mode)
Keywords: Chromatography, High performance liquid chromatography

HPLC Analysis of Nucleosides on Ascentis® Si (Silica)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Nucleosides on Ascentis® Si (Silica)
Keywords: Chromatography, High performance liquid chromatography

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

UHPLC/MS Analysis of 8-Hydroxy-2′-Deoxyguanosine and Related Compounds on Titan™ Silica

From our library of Articles, Sigma-Aldrich presents UHPLC/MS Analysis of 8-Hydroxy-2′-Deoxyguanosine and Related Compounds on Titan™ Silica
Keywords: Chromatography, Mass spectrometry, Separation

Peer-Reviewed Papers
15

References

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