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D8668 Sigma-Aldrich

2′-Deoxyadenosine monohydrate

powder, BioReagent, suitable for cell culture

Synonym: 9-(2-Deoxy-β-D-ribofuranosyl)adenine, Adenine deoxyriboside

  • CAS Number 16373-93-6

  • Empirical Formula (Hill Notation) C10H13N5O3 · H2O

  • Molecular Weight 269.26

  •  Beilstein/REAXYS Number 91015

  •  EC Number 213-488-7

  •  MDL number MFCD00005754

  •  PubChem Substance ID 24894112

  •  NACRES NA.75

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Properties

Related Categories Cell Culture, Miscellaneous Reagents and Supplements, Reagents and Supplements More...
InChI Key   OLXZPDWKRNYJJZ-RRKCRQDMSA-N
product line   BioReagent
form   powder
application(s)   cell culture | mammalian: suitable
solubility   H2O: soluble 25 mg/mL, clear to slightly hazy, colorless to faintly yellow
storage temp.   2-8°C

Description

Application

2′-Deoxyadenosine monohydrate has been used as a nucleotide precursor:
• To study the importance of homologous recombination at the interface between replication and mitosis
• To analyze deoxynucleoside-assisted transductions
• To study the effect of increased deoxycytidine on gemcitabine resistance in pancreatic cancer cells

2′-Deoxyadenosine monohydrate has been used for the preparation of deoxyribonucleoside stock solution for the anaerobic culture of Bacillus mojavensis strains including JF-2 and two Bacillus subtilis strains.

Packaging

1, 5 g in poly bottle

Biochem/physiol Actions

Excess 2′-deoxyadenosine gets converted to adenosine triphosphate (dATP), which inhibits ribonucleotide reductase.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
AU7358600

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

HPLC Analysis of Deoxyribonucleosides on Ascentis® Si

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Deoxyribonucleosides on Ascentis® Si
Keywords: Chromatography, High performance liquid chromatography

HPLC Analysis of Nucleosides on Ascentis® Si (Silica)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Nucleosides on Ascentis® Si (Silica)
Keywords: Chromatography, High performance liquid chromatography

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Peer-Reviewed Papers
15

References

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