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  • D8941 - 2,6-Difluoro-4-[2-(phenylsul­fonyl­amino)­ethyl­thio]­phenoxy­acet­amide

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D8941 Sigma-Aldrich

2,6-Difluoro-4-[2-(phenylsul­fonyl­amino)­ethyl­thio]­phenoxy­acet­amide

≥98% (HPLC), solid

Synonym: PEPA

  • CAS Number 141286-78-4

  • Empirical Formula (Hill Notation) C16H16N2O4S2F2

  • Molecular Weight 402.44

  •  MDL number MFCD04974493

  •  PubChem Substance ID 24278571

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Properties

Related Categories AMPA/Kainate Other, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
InChI Key   GTACSIONMHMRPD-UHFFFAOYSA-N
assay   ≥98% (HPLC)
form   solid
storage condition   protect from light
color   white
solubility   DMSO: >20 mg/mL
Gene Information   human ... GRIA1(2890), GRIA2(2891), GRIA3(2892), GRIA4(2893)

Description

Packaging

25 mg in poly bottle

5 mg in glass bottle

Biochem/physiol Actions

2,6-Difluoro-4-[2-(phenylsul­fonyl­amino)­ethyl­thio]­phenoxy­acet­amide is a structurally novel, selective, high affinity AMPA ionotropic glutamate receptor agonist that reduces ischemia-induced performance deficits in rats.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Making Headway

Milli-Q® Water Purification Solutions
Protocols & Articles
Peer-Reviewed Papers
15

References

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