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E5008 Sigma-Aldrich

[D-Ala2]-Leucine enkephalin

≥97% (HPLC)

Synonym: Tyr-D-Ala-Gly-Phe-Leu

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Enkephalins, Opioid Peptides, Peptides and Proteins,
Quality Level   200
assay   ≥97% (HPLC)
form   powder
application(s)   ligand binding assay: suitable
color   white
storage temp.   −20°C
SMILES string   CC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)C(C)NC(=O)C(N)Cc2ccc(O)cc2)C(O)=O
InChI   1S/C29H39N5O7/c1-17(2)13-24(29(40)41)34-28(39)23(15-19-7-5-4-6-8-19)33-25(36)16-31-26(37)18(3)32-27(38)22(30)14-20-9-11-21(35)12-10-20/h4-12,17-18,22-24,35H,13-16,30H2,1-3H3,(H,31,37)(H,32,38)(H,33,36)(H,34,39)(H,40,41)
InChI key   ZHUJMSMQIPIPTF-UHFFFAOYSA-N

Description

Amino Acid Sequence

Tyr-Ala-Gly-Phe-Leu

Packaging

5 mg in serum bottle

Biochem/physiol Actions

The Enkephalin amid peptide [D-Ala2]-Leucine enkephalin ((DADLE), a delta opioid agonist, is a degradation resistant long-acting Leu-enkephalin analog used to study the signaling pathway of delta opioid receptors.

Other Notes

Potent, long-acting Leu-enkephalin analog that is resistant to enzymatic degradation

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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