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F107 Sigma-Aldrich

Flunarizine dihydrochloride

Synonym: 1-[Bis(4-fluorophenyl)methyl]-4-(3-phenyl-2-propenyl)piperazine dihydrochloride

  • CAS Number 30484-77-6

  • Empirical Formula (Hill Notation) C26H26F2N2 · 2HCl

  • Molecular Weight 477.42

  •  Beilstein/REAXYS Number 4284243

  •  EC Number 250-216-6

  •  MDL number MFCD00058198

  •  PubChem Substance ID 329799673

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Properties

Related Categories Additional Standards, Analytical Standards, Analytical/Chromatography, Chemical Structure, Chromatography,
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
Featured Industry   Forensics and Toxicology
Veterinary
SMILES string   Cl[H].Cl[H].Fc1ccc(cc1)C(N2CCN(CC2)C\C=C\c3ccccc3)c4ccc(F)cc4
InChI   1S/C26H26F2N2.2ClH/c27-24-12-8-22(9-13-24)26(23-10-14-25(28)15-11-23)30-19-17-29(18-20-30)16-4-7-21-5-2-1-3-6-21;;/h1-15,26H,16-20H2;2*1H/b7-4+;;
InChI key   RXKMOPXNWTYEHI-RDRKJGRWSA-N

Description

Biochem/physiol Actions

Blocks T-type Ca2+/Na+ channels; inhibits K+-induced catecholamine release from chromaffin cells

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
TK9187000

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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F8257 Flunarizine dihydrochloride, ≥98% (TLC)

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