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F3388 Sigma-Aldrich

Ferric citrate

BioReagent, suitable for cell culture

Synonym: Iron(III) citrate hydrate, Iron(III) citrate

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Properties

Related Categories Cell Culture, Miscellaneous Reagents and Supplements, Reagents and Supplements More...
Quality Level   200
biological source   synthetic (organic)
product line   BioReagent
application(s)   cell culture | mammalian: suitable
solubility   hot water: 0.01 g/mL, clear, orange-yellow
shipped in   ambient
storage temp.   room temp
SMILES string   OC12CC(=O)O[Fe](OC(=O)C1)OC2=O
InChI   1S/C6H8O7.Fe/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);/q;+3/p-3
InChI key   NPFOYSMITVOQOS-UHFFFAOYSA-K

Description

Application

Ferric citrate provides a source of iron used in cell culture applications. It provides iron in a less toxic form than free iron salts. Ferric citrate has been used as medium supplement in human osteosarcoma cell (U2OS) culture, human embryonic kidney (HEK293) cells and adult primary cardiomyocytes.

Packaging

1 kg in poly bottle

250 g in poly bottle

Biochem/physiol Actions

Ferric citrate is used as a component of protein-free medium. It is used as a substitute for transferrin in mouse hybridomas culture. Ferric citrate enhances IgM production. It indirectly stimulates the mitogen-activated protein kinase (MAPK) by favoring high amphiregulin oncoprotein levels in colon cancer.  Ferric citrate is effective in binding to phosphate in patients with dialysis-dependent chronic kidney disease.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

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Peer-Reviewed Papers
15

References

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