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F8507 Sigma-Aldrich

(±)-Fenfluramine hydrochloride

Synonym: (±)-N-Ethyl-α-methyl-m-[trifluoromethyl]phenethylamine hydrochloride

  • CAS Number 16105-77-4

  • Empirical Formula (Hill Notation) C12H16F3N · HCl

  • Molecular Weight 267.72

  •  MDL number MFCD00058016

  •  PubChem Substance ID 24894965

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Neurobiology, Neuroscience, Neurotransmission (Obesity),
drug control   USDEA Schedule IV
Featured Industry   Forensics and Toxicology
SMILES string   Cl.CCNC(C)Cc1cccc(c1)C(F)(F)F
InChI   1S/C12H16F3N.ClH/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15;/h4-6,8-9,16H,3,7H2,1-2H3;1H
InChI key   ZXKXJHAOUFHNAS-UHFFFAOYSA-N
Gene Information   human ... HTR1D(3352), HTR2C(3358), SIGMAR1(10280)

Description

Biochem/physiol Actions

Neurotoxic on prolonged administration or at high dosage; releases serotonin from axon terminals by a nonexocytotic mechanism; anorectic

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
WGK 3
RTECS 
DA0295500
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

History of Biogenic Amine Use for Treating Obesity

The discovery of ephedrine (Product No. E2750) in the 1930s led to the synthesis of amphetamines. Initially utilized as stimulants, they were soon shown to exhibit food intake and appetite suppressin...
Keywords: Obesity

Peer-Reviewed Papers
15

References

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