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Adenosine 5′-triphosphate (ATP) disodium salt hydrate

vial of ~1 mg ATP

Synonym: ATP disodium hydrate

  • CAS Number 34369-07-8

  • Linear Formula C10H14N5O13P3Na2 · xH2O

  • Molecular Weight 551.14 (anhydrous basis)

  •  EC Number 213-579-1

  •  MDL number MFCD00150755

  •  eCl@ss 32160414

  •  PubChem Substance ID 24895005

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Properties

Related Categories Analytical and Industrial Enzymes, Biochemicals and Reagents, Enzymes, Inhibitors, and Substrates, Kits and Reagents for ATP Determination, Luciferase More...
InChI Key   NTBQNWBHIXNPRU-MSQVLRTGSA-L
form   lyophilized powder
packaging   vial of ~1 mg ATP
storage temp.   −20°C

Description

Packaging

1 vial in glass bottle

Preparation Note

Prepared to be substantially vanadium-free.

Quantity

Each vial contains ~1.2 mg of Na2ATP • 3H2O equivalent to ~1.0 mg of ATP (2.0 μmol). Actual amount printed on the label.

Application

Adenosine 5′-triphosphate (ATP) disodium salt hydrate has been:
• used as a standard to measure ATP by bioluminescence method
• used in kinase buffer to assess the interaction between death-associated protein kinases (DAPK2) and 14-3-3-β
• used as a standard in ATP colorimetric assay

Biochem/physiol Actions

Adenosine 5′-triphosphate (ATP) is one of the nucleoside triphosphate present in living system. It controls various biologic processes such as glucose metabolism, muscle contraction and neurotransmission. Apart from this, ATP serves as an important energy source for the cell. Administration of ATP might be useful in the treatment of non-small-cell lung cancer.

Adenosine 5′-triphosphate was shown to have inhibitory effects on the inflammatory response by abrogating secretion of TNF-α and promoting secretion of Interleukin-10.

P2 purinergic agonist; increases activity of Ca2+-activated K+ channels; substrate for ATP-dependent enzyme systems

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
AU7417000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

HPLC Analysis of Adenosine Nucleosides on Supelcosil™ LC-18-T

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Adenosine Nucleosides on Supelcosil™ LC-18-T
Keywords: Chromatography, High performance liquid chromatography, Separation

Peer-Reviewed Papers
15

References

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