G0668 Sigma-Aldrich


≥98% (HPLC), solid

Synonym: N4-(1-Benzyl-1H-indazol-5-yl)-N6,N6-dimethyl-pyrido­[3,4-d]­pyrimidine-4,6-diamine

  • CAS Number 202272-68-2

  • Empirical Formula (Hill Notation) C23H21N7

  • Molecular Weight 395.46

  •  MDL number MFCD04974495

  •  PubChem Substance ID 24278451

  •  NACRES NA.77




50, 250 mg in glass bottle

Biochem/physiol Actions

Potent and selective dual inhibitor of EGFR (IC50 = 0.016 mM) and ErbB-2 receptor tyrosine kinase.

Features and Benefits

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Legal Information

Sold for research purposes under agreement from Glaxo­Smith­Kline

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 


Certificate of Analysis (COA)

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Protocols & Articles


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Discover Bioactive Small Molecules for Kinase Phosphatase Biology

Phosphorylation is a ubiquitous cellular regulatory mechanism that mediates signal transduction pathways, which carry signals from the cell surface to the nucleus or cytoplasm, by altering the activi...
Keywords: Apoptosis, Bioactive small molecules, Cancer, Diseases, Inflammation, Metabolism, Neurodegenerative Diseases, Phosphorylations, Transduction

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