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G2879 Sigma-Aldrich

Glycine hydrochloride

≥99% (HPLC)

Synonym: Aminoacetic acid, Aminoethanoic acid, Glycocoll

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, GABA and Glycine Receptor Modulators, Glycinergics, Ion Channels,
InChI Key   IVLXQGJVBGMLRR-UHFFFAOYSA-N
assay   ≥99% (HPLC)
mp   176-180 °C (lit.)

Description

Biochem/physiol Actions

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Packaging

1 kg in poly bottle

100, 500 g in poly bottle

Application

Glycine hydrochloride has been used as a component of Ag (silver)-stripping buffer for multiplex immunohistochemistry in mice tissues.

General description

Glycine is an inhibitory amino acid neurotransmitter that only acts on receptors which bring out an enhanced chloride conductance. It shows highest concentrations in the spinal cord as compared to elsewhere in the brain. However, it interacts with and allostericaly activates the excitatory receptor N-methyl-D-aspartate (NMDA), thus, resulting in excitatory transmission in brain.

Safety & Documentation

Safety Information

Symbol 
GHS05  GHS05
Signal word 
Danger
Hazard statements 
RIDADR 
UN 3261 8 / PGII
WGK Germany 
1
RTECS 
MC0560000

Milli-Q® Water Purification Solutions
Protocols & Articles

Protocols

Stripping and Reprobing Western Blotting Membranes

Western blotting is a commonly used technique for studying protein function and localization. Typically, protein samples are separated by SDS-PAGE and transferred to a nitrocellulose or PVDF membrane...
Keywords: Buffers, Detergents, Immobilization, PAGE, Western blot

Peer-Reviewed Papers
15

References

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