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G5889 Sigma-Aldrich

L-Glutamic acid monosodium salt hydrate

BioReagent, suitable for cell culture, suitable for insect cell culture, ≥99%

Synonym: (S)-2-Aminopentanedioic acid, L-Glutamic acid monosodium salt, Glu, MSG, Monosodium glutamate

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Properties

Related Categories Amino Acids, Amino Acids and Vitamins, Cell Culture, Companion Products and Reagents, Insect Platform,
Quality Level   200
product line   BioReagent
assay   ≥99%
form   powder
application(s)   cell culture | insect: suitable
  cell culture | mammalian: suitable
color   white to off-white
mp   163 °C
InChI   1S/C5H9NO4.Na.H2O.H/c6-3(5(9)10)1-2-4(7)8;;;/h3H,1-2,6H2,(H,7,8)(H,9,10);;1H2;
InChI key   JYDGDQPVBSBYRT-UHFFFAOYSA-N

Description

General description

L-Glutamic acid/monosodium glutamate (MSG) is the sodium salt of glutamic acid. It is a commonly used food additive.

Application

L-Glutamic acid monosodium salt hydrate has been used:
• to prepare glutamate stock solution in HEPES-buffered saline (HBS) for glutamate perfusions
• as a component in YNG (yeast nitrogen base glutamate) medium
• used to treat HT22 hippocampal cells to study its effects on cell viability and to examine the expression of molecules related to apoptotic cell death
• as a component of fresh media to culture neurons and to assess glutamate uptake

Packaging

1 kg in poly bottle

100, 500 g in poly bottle

Biochem/physiol Actions

Monosodium glutamate (MSG) is a food additive and an environmental agent, that can affect inflammation.

Agonist at kainate, NMDA, and quisqualate receptors; an excitatory amino acid neurotransmitter.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

Bile Acids

The liver excretes excess cholesterol in the form of bile acids. Bile acids serve two purposes: to remove unwanted cholesterol from the body and to aid in lipid digestion in the intestine. Bile acids...
BioFiles 2007, 2.7, 17.
Keywords: Absorption, Digestions, Transcription

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Cell Culture Troubleshooting Guide

Cell culture has become one of the most fundamental techniques for modeling biological systems, and is of increasing importance in the biotechnology and pharmaceutical sectors as well as an essential...
Keywords: Antibiotics, Apoptosis, Cell attachment, Cell culture, Cryopreservation, Filtration, Growth factors, Pharmaceutical, Phase transitions

Peer-Reviewed Papers
15

References

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