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H1635 Sigma-Aldrich

N-Hippuryl-His-Leu hydrate

powder, ≥98% (HPLC)

Synonym: N-Benzoyl-Gly-His-Leu, N-Hippuryl-L-histidyl-L-leucine hydrate

  • CAS Number 207386-83-2

  • Empirical Formula (Hill Notation) C21H27N5O5 · xH2O

  • Molecular Weight 429.47 (anhydrous basis)

  •  Beilstein/REAXYS Number 5664178

  •  EC Number 250-597-9

  •  MDL number MFCD00149318

  •  PubChem Substance ID 24895469

  •  NACRES NA.32

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Properties

Related Categories Angiotensin Converting Enzyme, Angiotensin Metabolism, Angiotensins, Biochemicals and Reagents, Cell Biology,
assay   ≥98% (HPLC)
form   powder
color   white to off-white
solubility   acetic acid: ~50 mg/mL
storage temp.   −20°C
SMILES string   O.CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)c2ccccc2)C(O)=O
InChI   1S/C21H27N5O5.H2O/c1-13(2)8-17(21(30)31)26-20(29)16(9-15-10-22-12-24-15)25-18(27)11-23-19(28)14-6-4-3-5-7-14;/h3-7,10,12-13,16-17H,8-9,11H2,1-2H3,(H,22,24)(H,23,28)(H,25,27)(H,26,29)(H,30,31);1H2/t16-,17-;/m0./s1
InChI key   NWOJMNXIJBZMPK-QJHJCNPRSA-N
Gene Information   human ... ACE(1636), ACE2(59272)
mouse ... ACE3(217246)
rat ... ACE(11421), ACE2(70008), ACE3(498012)

Description

Amino Acid Sequence

NBz-Gly-His-Leu

Packaging

1 g in poly bottle

25, 100, 500 mg in poly bottle

Substrates

Substrate for angiotensin converting enzyme.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

Antihypertensive Agents

Agents that inhibit angiontensin-converting enzymes (ACE) and angiotensin II formation are essential to cardiovascular medicine.1 These inhibitors are used not only to treat essential hypertension an...
Sami Barghshoon
BioFiles v7 n5, 2012, 5–20
Keywords: AGE, Antihypertensives, Cardiovascular, Clinical, Diuretics, PAGE, Reductions

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