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H6034 Sigma-Aldrich

L-Histidine

suitable for cell culture, meets EP, USP testing specifications, from non-animal source

Synonym: (S)-2-Amino-3-(4-imidazolyl)propionic acid, NSC 137773

  • CAS Number 71-00-1

  • Empirical Formula (Hill Notation) C6H9N3O2

  • Molecular Weight 155.15

  •  Beilstein/REAXYS Number 84088

  •  EC Number 200-745-3

  •  MDL number MFCD00064315

  •  eCl@ss 32160406

  •  PubChem Substance ID 24895728

  •  NACRES NA.26

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Properties

Related Categories Allium cepa (Onion), Allium sativum (Garlic), Aloe Vera, Amino Acids, Amino Acids & Derivatives,
Quality Level   200
biological source   non-animal source
assay   98.5-101.0%
form   powder
application(s)   cell culture | mammalian: suitable
  peptide synthesis: suitable
impurities   endotoxin, tested
color   white to off-white
mp   282 °C (dec.) (lit.)
solubility   H2O: 50 mg/mL
suitability   meets EP, USP testing specifications
Featured Industry   Pharmaceutical (small molecule)
storage temp.   room temp
SMILES string   N[C@@H](Cc1c[nH]cn1)C(O)=O
InChI   1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1
InChI key   HNDVDQJCIGZPNO-YFKPBYRVSA-N
Gene Information   human ... CA1(759), CA2(760)

Description

Application

L-histidine has been used as a component in agar plates containing 5-fluorocytosine (5-FC) for the selection of yeast transformants. It has also been used as a component of adult mouse keratinocyte growth medium.

Packaging

1 kg in poly bottle

10 mg in glass bottle

25, 100 g in poly bottle

Biochem/physiol Actions

L-Histidine is an essential amino acid that binds to metal ions and may aid in the transport of copper. Histidine is widely present at the active sites of enzymes. It also has a role in binding of heme groups, macromolecules and phosphate groups in the binding sites of proteins.

Precursor of histamine by action of histidine decarboxylase.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Related Content

Amino Acids Reference Charts

Amino acids are the compounds or building blocks that make up peptides and proteins. Each amino acid is structured from an amino group and a carboxyl group bound to a tetrahedral carbon. This carbon ...
Keywords: Building blocks, Gene expression, Mass spectrometry

Peer-Reviewed Papers
15

References

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