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H6647 Sigma-Aldrich

L-Histidinol dihydrochloride

≥98 (TLC)

Synonym: β-Aminoimidazole-4-propanol dihydrochloride, (S)-2-Amino-3-(4-imidazolyl)propanol dihydrochloride

  • CAS Number 1596-64-1

  • Empirical Formula (Hill Notation) C6H11N3O · 2HCl

  • Molecular Weight 214.09

  •  Beilstein/REAXYS Number 3914853

  •  EC Number 216-482-2

  •  MDL number MFCD00078058

  •  PubChem Substance ID 24895755

  •  NACRES NA.32

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Properties

Related Categories Amino Acid, Cell Biology, Cell Signaling and Neuroscience, Histaminergics, Metabolic Pathways,
Quality Level   200
assay   ≥98 (TLC)
form   powder
application(s)   cell analysis: suitable
color   white to off-white
mp   198-201 °C (dec.) (lit.)
SMILES string   Cl[H].Cl[H].N[C@H](CO)Cc1c[nH]cn1
InChI   1S/C6H11N3O.2ClH/c7-5(3-10)1-6-2-8-4-9-6;;/h2,4-5,10H,1,3,7H2,(H,8,9);2*1H/t5-;;/m0../s1
InChI key   FRCAFNBBXRWXQA-XRIGFGBMSA-N
Gene Information   human ... HRH1(3269)
mouse ... HRH1(15465)
rat ... HRH1(24448)

Description

Application

L-Histidinol dihydrochloride has been used:
• as a reagent in urinary metabolite analysis
• for making DT40 knockout cells, where cells were selected in 1mg/ml histidinol
• for inducing amino acid deprivation in HepG2 cells

Packaging

1, 5 g in poly bottle

10 mg in glass bottle

Biochem/physiol Actions

Precursor of histamine; reversible inhibitor of protein synthesis.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. H6647.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Target organs 
Respiratory system
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
NI8260000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles

Articles

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

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