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I1007 Sigma-Aldrich

6-(Iodoacetamido)hexanoic acid N-hydroxysuccinimide ester

powder

  • CAS Number 134759-23-2

  • Empirical Formula (Hill Notation) C12H17IN2O5

  • Molecular Weight 396.18

  •  MDL number MFCD00132999

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Properties

form   powder
solubility   methanol: 50 mg/mL
  DMF: soluble
storage temp.   −20°C

Description

Application

A heterobifunctional cross-linking reagent containing an extended spacer with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5) Second coupling specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 7.5 (7.0-8.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Provides a 9-atom linker.

Caution

The iodoacetyl group is light sensitive.

Safety & Documentation

Safety Information

WGK Germany 
3

Documents

Certificate of Analysis

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Protocols & Articles
Peer-Reviewed Papers
15

References

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