• USA Home
  • I2250 - Indole-5-carboxylic acid

EMAIL THIS PAGE TO A FRIEND
I2250 Sigma-Aldrich

Indole-5-carboxylic acid

~95% (TLC)

Synonym: 5-Carboxyindole

  • CAS Number 1670-81-1

  • Empirical Formula (Hill Notation) C9H7NO2

  • Molecular Weight 161.16

  •  Beilstein/REAXYS Number 124391

  •  EC Number 216-799-6

  •  MDL number MFCD00005678

  •  PubChem Substance ID 24895968

Purchase

Properties

assay   ~95% (TLC)
mp   211-213 °C (lit.)
storage temp.   −20°C
SMILES string   OC(=O)c1ccc2[nH]ccc2c1
InChI   1S/C9H7NO2/c11-9(12)7-1-2-8-6(5-7)3-4-10-8/h1-5,10H,(H,11,12)
InChI key   IENZCGNHSIMFJE-UHFFFAOYSA-N

Description

Application

• Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, as potential anticancer immunomodulators
• Reactant for preparation of indolyl-quinolines via metal- and solvent-free autoxidative coupling reaction
• Reactant for preparation of anthranilic acids using bromamine-B oxidant and palladium chloride catalyst
• Reactant for synthesis of indirubin derivatives
• Reactant for preparation of amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway
• Reactant for preparation of piperazine-bisamide analogs as human growth hormone secretagogue receptor antagonists for treatment of obesity

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Related Products

replaced by

Product #

Description

Add to Cart

I5400 Indole-5-carboxylic acid, 99%

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?