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I7125 Sigma-Aldrich

5-Iodo-2′-deoxyuridine

≥99% (HPLC)

Synonym: 1-(2-Deoxy-β-D-ribofuranosyl)-5-iodouracil, 2′-Deoxy-5-iodouridine, 5-IUdR, IDU, IdUrd, Idoxuridine

  • CAS Number 54-42-2

  • Empirical Formula (Hill Notation) C9H11IN2O5

  • Molecular Weight 354.10

  •  Beilstein/REAXYS Number 30397

  •  EC Number 200-207-8

  •  MDL number MFCD00134656

  •  PubChem Substance ID 57654307

  •  NACRES NA.51

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Properties

Related Categories Biochemicals and Reagents, Nucleosides, Nucleosides, Nucleotides, Oligonucleotides More...
Quality Level   200
assay   ≥99% (HPLC)
form   powder or crystals
mp   194 °C (lit.)
solubility   1 N NH4OH: 50 mg/mL, clear to very slightly hazy, colorless to light yellow
storage temp.   2-8°C
SMILES string   OC[C@H]1O[C@H](C[C@@H]1O)N2C=C(I)C(=O)NC2=O
InChI   1S/C9H11IN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
InChI key   XQFRJNBWHJMXHO-RRKCRQDMSA-N

Description

Application

5-Iodo-2′-deoxyuridine (5-IUdR; IdUrd) is a pyrimidine analog (halogenated thymidine) that has antiviral activity agains vaccinia virus (orthopoxviruses). IdUrd is used as a radiosensitizer in human cancer studies.

Packaging

5, 25 g in glass bottle

Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Target organs 
Respiratory system
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
YU7700000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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