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I9910 Sigma-Aldrich

Ibutilide hemifumarate salt

≥98% (HPLC)

Synonym: (±)-N-[4-[4-(Ethylheptylamino)-1-hydroxybutyl]phenyl]-methanesulfonamide hemifumarate salt, Corvert

  • CAS Number 122647-32-9

  • Empirical Formula (Hill Notation) C20H36N2O3S · 0.5C4H4O4

  • Molecular Weight 442.61

  •  MDL number MFCD01715410

  •  PubChem Substance ID 329815470

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Properties

Related Categories Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
InChI Key   PCIOHQNIRPWFMV-WXXKFALUSA-N
assay   ≥98% (HPLC)
form   solid
color   off-white to tan
solubility   H2O: >20 mg/mL
originator   Pfizer
storage temp.   room temp

Description

Packaging

10, 50 mg in glass bottle

Biochem/physiol Actions

Ibutilide hemifumarate salt is considered a new generation "pure" Class III antiarrhythmic agent. Ibutilide binds to and alters the activity of hERG potassium channels, delayed inward rectifier potassium (IKr) channels and L-type (dihydropyridine sensitive) calcium channels.

Features and Benefits

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Pfizer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
1

Documents

Certificate of Analysis

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Making Headway

Milli-Q® Water Purification Solutions
Protocols & Articles

Articles

Antihypertensive Agents

Download BioFiles v7 n5 (3.18 Mb PDF) Back to Pharmaceutical Drugs and Drug Candidates homepage
Sami Barghshoon
BioFiles v7 n5, 2012, 5–20
Keywords: AGE, Antihypertensives, Cardiovascular, Clinical, Diuretics, PAGE, Pharmaceutical, Reductions

Discover Bioactive Small Molecules for Ion Channels Research

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Peer-Reviewed Papers
15

References

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