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J3770 Sigma-Aldrich

JNJ7777120

≥98% (HPLC)

Synonym: 1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methyl-piperazine

  • CAS Number 459168-41-3

  • Empirical Formula (Hill Notation) C14H16N3OCl

  • Molecular Weight 277.75

  •  MDL number MFCD04343337

  •  PubChem Substance ID 329815408

  •  NACRES NA.77

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Properties

Related Categories Antagonists- Histaminergics, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents,
Quality Level   100
assay   ≥98% (HPLC)
form   solid
color   white to off-white
solubility   DMSO: >20 mg/mL
  H2O: insoluble
originator   Johnson & Johnson
storage temp.   room temp
SMILES string   CN1CCN(CC1)C(=O)c2cc3cc(Cl)ccc3[nH]2
InChI   1S/C14H16ClN3O/c1-17-4-6-18(7-5-17)14(19)13-9-10-8-11(15)2-3-12(10)16-13/h2-3,8-9,16H,4-7H2,1H3
InChI key   HUQJRYMLJBBEDO-UHFFFAOYSA-N

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

JNJ7777120 is a potent, selective non-imidazole H4 histamine receptor antagonist.

Features and Benefits

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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