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J4250 Sigma-Aldrich

JKC 302

≥97% (HPLC)

Synonym: cyclo(D-Ser-Pro-D-Val-Leu-D-Trp)

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Properties

Related Categories Antagonists, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Endothelin - Receptor Antagonists,
assay   ≥97% (HPLC)
storage temp.   −20°C
SMILES string   CC(C)C[C@@H]1NC(=O)[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@@H](CO)NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC1=O)C(C)C
InChI   1S/C30H42N6O6/c1-16(2)12-21-26(38)32-22(13-18-14-31-20-9-6-5-8-19(18)20)27(39)34-23(15-37)30(42)36-11-7-10-24(36)28(40)35-25(17(3)4)29(41)33-21/h5-6,8-9,14,16-17,21-25,31,37H,7,10-13,15H2,1-4H3,(H,32,38)(H,33,41)(H,34,39)(H,35,40)/t21-,22+,23+,24-,25+/m0/s1
InChI key   FLVWONZBLRGQPK-VCDBXAJLSA-N

Description

Biochem/physiol Actions

JKC-302 may be used as an endothelin receptor (eta) antagonist similar to JKC-301 and other cyclic D-amino acid containing pentapeptides.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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