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L6152 Sigma-Aldrich

D-Luciferin

synthetic, BioXtra, ≥99% (HPLC)

Synonym: (S)-2-(6-Hydroxy-2-benzothiazolyl)-2-thiazoline-4-carboxylic acid, 4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid, Firefly Luciferin

  • CAS Number 2591-17-5

  • Empirical Formula (Hill Notation) C11H8N2O3S2

  • Molecular Weight 280.32

  •  Beilstein Registry Number 30484

  •  EC Number 219-981-3

  •  MDL number MFCD00042929

  •  PubChem Substance ID 24896428

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Properties

Related Categories Analytical and Industrial Enzymes, Biochemicals and Reagents, Chemiluminescent compounds, Enzyme Substrates, Enzymes, Inhibitors, and Substrates,
biological source   synthetic
InChI Key   BJGNCJDXODQBOB-SSDOTTSWSA-N
product line   BioXtra
assay   ≥99% (HPLC)
storage temp.   −20°C

Description

Application

Substrate for firefly luciferase with a Km of approx 2 μM.

Linkage

Highly purified grade with reduced levels of inhibitor relative to L 9504

Packaging

1, 10 mg in glass bottle

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

ABC Transporters and Cancer Drug Resistance

Chemotherapy is the treatment of choice against many types of cancer. However, over time chemotherapeutic drugs can become less effective due to the development of resistance that involves a group of...
BioFiles 2007, 2.4, 7.
Keywords: Absorption, Cancer, Clinical, Cloning, Combinatorial synthesis, Diseases, Enzymology, Gene expression, Genetic, Immunology, Pharmaceutical, Reductions, Transfection

HPLC Analysis of Luciferin Enantiomers on Astec® CHIROBIOTIC® V

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Luciferin Enantiomers on Astec® CHIROBIOTIC® V
Keywords: Chromatography, High performance liquid chromatography

HPLC Analysis of Luciferin Enantiomers on CHIRALPAK® AGP

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Luciferin Enantiomers on CHIRALPAK® AGP
Keywords: Chromatography, High performance liquid chromatography, Vitamins

TokeOni: Properties and Applications

Bioluminescence imaging (BLI) systems allow for high-sensitive and noninvasive monitoring of cell proliferation, activity of signaling pathways and protein-protein interactions in living tissues.1-3 ...
Takahiro Kuchimaru and Shinae Kizaka-Kondoh
Graduate School of Bioengineering & Biotechnology, Tokyo Institute of Technology, Yokohama, Japan.
Keywords: Cancer, Cell proliferation, Infrared spectroscopy

Protocols

Bioluminescence imaging of hollow fibers in living animals: its application in monitoring molecular pathways

Guo-Jun Zhang a , Tsing-Bau Chen a , Richard Hargreaves a , Cyrille Sur a , David L Williams a
Keywords: Angiogenesis, Antibiotics, Antitumor agents, Apoptosis, Cancer, Cell culture, Cell proliferation, Cellular processes, Clinical, Culture media, Drug discovery, Gene expression, Inflammation, Pharmaceutical, Phase transitions, Recombination, Sterilizations, Transcription, Transfection, Ubiquitinations

Peer-Reviewed Papers
15

References

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