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L7875 Sigma-Aldrich

DL-Leucine

≥99% (HPLC)

Synonym: (±)-Amino-4-methylpentanoic acid

  • CAS Number 328-39-2

  • Linear Formula (CH3)2CHCH2CH(NH2)CO2H

  • Molecular Weight 131.17

  •  Beilstein/REAXYS Number 636005

  •  EC Number 206-328-2

  •  MDL number MFCD00063087

  •  PubChem Substance ID 24896484

  •  NACRES NA.26

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Properties

Related Categories Amino Acids, Amino Acids & Derivatives, Biochemicals and Reagents, Chemical Biology, Chemical Synthesis,
Quality Level   200
assay   ≥99% (HPLC)
form   powder
application(s)   detection: suitable
  peptide synthesis: suitable
color   white
mp   293-296 °C (subl.) (lit.)
solubility   1 M HCl: soluble
SMILES string   CC(C)CC(N)C(O)=O
InChI   1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)
InChI key   ROHFNLRQFUQHCH-UHFFFAOYSA-N

Description

Application

DL-Leucine is a racemic mixture of the D- and L- enantiomers of Leucine. DL-Leucine is used to form benzimidazole and pyrimidine hydroxy azo dyes with various transition metals. DL-Leucine may be used for the evaluation of chiral amino acid separation techniques.

DL-Leucine is used for the following applications:
• Used as a standard for the measurement of free amino acids
• Used in the process of tritiated leucine uptake
• Used in solution preparation (various organics were used in different combinations and concentrations to model complex surface tension effects, DL-Leucine is one of them). It is chosen due to its presence in atmospheric aerosols and ice nucleation activity as well as for its surfactant character

Packaging

25, 100 g in poly bottle

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

HPLC Analysis of Leucine Enantiomers on Astec® CHIROBIOTIC® T (23 °C)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Leucine Enantiomers on Astec® CHIROBIOTIC® T (23 °C)
Keywords: Chromatography, High performance liquid chromatography

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Related Content

Amino Acids Reference Charts

Amino acids are the compounds or building blocks that make up peptides and proteins. Each amino acid is structured from an amino group and a carboxyl group bound to a tetrahedral carbon. This carbon ...
Keywords: Building blocks, Gene expression, Mass spectrometry

Peer-Reviewed Papers
15

References

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