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M1380 Sigma-Aldrich

N6-Monobutyryladenosine 3′:5′-cyclic monophosphate sodium salt

Synonym: 6MB-cAMP

  • CAS Number 70253-67-7

  • Empirical Formula (Hill Notation) C14H17N5NaO7P

  • Molecular Weight 421.28

  •  MDL number MFCD00057135

  •  PubChem Substance ID 24896638

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Properties

Related Categories Biochemicals and Reagents, Nucleosides, Nucleotides, Oligonucleotides, Nucleotide Analogs More...
InChI Key   RHNOUOJKQVKESB-UHFFFAOYSA-N
storage temp.   −20°C

Description

Application

N6-Monobutyryladenosine 3′:5′-cyclic monophosphate sodium salt is suitable:
• to test the hypothesis that it stimulates the long-lasting potentiation of post ganglionic response
• as protein kinase A activator, in human primary cultured thyrocytes for analyzing the modulations in cAMP cascade regulated gene expression
• to analyse its effect on progesterone production in corpus luteum isolated from pseudopregnant rabbits

Biochem/physiol Actions

Membrane permeable analog of cAMP that activates protein kinase A and is resistant to degradation by phosphodiesterase

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Certificate of Origin

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Protocols & Articles
Peer-Reviewed Papers
15

References

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