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M7772 Sigma-Aldrich

8-Mercaptoguanosine

crystalline

Synonym: 8-Thioguanosine

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Properties

form   crystalline
color   light yellow
storage temp.   2-8°C
SMILES string   NC1=NC(=O)C2=C(N1)N(C3OC(CO)C(O)C3O)C(=S)N2

Description

Biochem/physiol Actions

8-Mercaptoguanosine is used to stimulate gene activation; in CD38-activated B cells it induces activation-induced cytidine deaminase (AID) expression. 8-Mercaptoguanosine is also used as an inhibitor of enzymes such as GTP cyclohydrolase I.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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