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M9149 Sigma-Aldrich

Mepartricin

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Properties

Related Categories Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics G-M, Antibiotics by Mechanism of Action,
potency   3700 units Mepartricin per mg
color   yellow to yellow with tan cast powder
solubility   DMF: 50 mg/mL, slightly hazy, red to red-brown
Mode of action   cell wall synthesis | interferes
antibiotic activity spectrum   fungi
storage temp.   2-8°C
SMILES string   COC(=O)C1C(O)CC2(O)CC(O)CC(O)CC(O)CC(O)CC(=O)CC(O)CC(=O)OC(C(C)CCC(O)CC(=O)c3ccc(N)cc3)C(C)\C=C\C=C\C=C\C=C\C=C\C=C\C=C\C(CC1O2)O[C@@H]4O[C@H](C)[C@@H](O)[C@H](N)[C@@H]4O
InChI   1S/C59H86N2O19/c1-35-17-15-13-11-9-7-5-6-8-10-12-14-16-18-47(78-58-55(73)53(61)54(72)37(3)77-58)32-50-52(57(74)76-4)49(70)34-59(75,80-50)33-46(68)29-44(66)27-42(64)25-41(63)26-43(65)28-45(67)31-51(71)79-56(35)36(2)19-24-40(62)30-48(69)38-20-22-39(60)23-21-38/h5-18,20-23,35-37,40-42,44-47,49-50,52-56,58,62-64,66-68,70,72-73,75H,19,24-34,60-61H2,1-4H3/b6-5+,9-7+,10-8+,13-11+,14-12+,17-15+,18-16+/t35?,36?,37-,40?,41?,42?,44?,45?,46?,47?,49?,50?,52?,53+,54-,55+,56?,58+,59?/m1/s1
InChI key   GIDIUOCSTCGLRW-QJSPMWJNSA-N

Description

General description

Chemical structure: macrolide

Application

Mepartricin is a polyene antibacterial with antifungal and antiprotozoal activity. It is an Amphotericin B(AmB) analogue and has been used to study scrapie. It is used as an antibiotic supplement in cell culture.

Mepartricin is used in studies on sterol biosynthesis and bacterial cell membranes. It may be incorporated into liposomes

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
RW5692000

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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