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M9429 Sigma-Aldrich

Menadione

meets USP testing specifications

Synonym: 2-Methyl-1,4-naphthoquinone, Vitamin K3

  • CAS Number 58-27-5

  • Empirical Formula (Hill Notation) C11H8O2

  • Molecular Weight 172.18

  •  Beilstein/REAXYS Number 1908453

  •  EC Number 200-372-6

  •  MDL number MFCD00001681

  •  PubChem Substance ID 24897335

  •  NACRES NA.21

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Properties

Related Categories Analytical/Chromatography, Biochemicals and Reagents, Core Bioreagents, Lipids, Pharmacopoeia,
biological source   synthetic (organic)
InChI Key   MJVAVZPDRWSRRC-UHFFFAOYSA-N
assay   98.5-101.0% dry basis
form   solid
mp   105-107 °C (lit.)
suitability   meets USP testing specifications
Featured Industry   Pharmaceutical (small molecule)
Gene Information   human ... NQO1(1728)

Description

General description

Menadione (Vitamin K3) is the synthetic form of vitamin K. It has the structure similar to vitamin K1 and K2. Vitamin K1, K2 and K3 are biologically active. Water soluble forms of menadiones are used in swine and poultry diets.

Application

Menadione has been used:
• to treat HL-60 cells as positive control for apoptosis for flow cytometry
• as an oxidative stress inducer in transgenic embryos after 24 h of post fertilization
• to treat HaCaT cell line, for quantifying total and oxidised glutathione

Packaging

25, 100 g in glass bottle

Biochem/physiol Actions

Menadione is an oxidative stress inducer.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
QL9100000

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Single- & multi-channel pipettes from BRAND
Protocols & Articles
Peer-Reviewed Papers
15

References

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