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N151 Sigma-Aldrich

Nisoxetine hydrochloride

solid, ≥98% (HPLC)

Synonym: (±)-γ-(2-Methoxyphenoxy)-N-methyl-benzenepropanamine hydrochloride, LY-94,939

  • CAS Number 57754-86-6

  • Empirical Formula (Hill Notation) C17H21NO2 · HCl

  • Molecular Weight 307.82

  •  MDL number MFCD00153850

  •  PubChem Substance ID 24277788

  •  NACRES NA.77

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, Biogenic Amine Transport Inhibitors, Cell Biology,
Quality Level   100
assay   ≥98% (HPLC)
form   solid
color   white to beige
solubility   H2O: 20 mg/mL
  ethanol: 50 mg/mL
SMILES string   Cl[H].CNCCC(Oc1ccccc1OC)c2ccccc2
InChI   1S/C17H21NO2.ClH/c1-18-13-12-15(14-8-4-3-5-9-14)20-17-11-7-6-10-16(17)19-2;/h3-11,15,18H,12-13H2,1-2H3;1H
InChI key   LCEURBZEQJZUPV-UHFFFAOYSA-N

Description

Packaging

25, 100 mg in glass bottle

Biochem/physiol Actions

Potent and selective inhibitor of the norepinephrine transporter (Ki = 5.1 nM).

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Legal Information

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Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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