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  • N1627 - 4-Nitrophenyl β-D-glucuronide

N1627 Sigma-Aldrich

4-Nitrophenyl β-D-glucuronide

≥98% (TLC)

Synonym: 4-Nitrophenyl-β-D-glucopyranosiduronic acid, PNPG

  • CAS Number 10344-94-2

  • Empirical Formula (Hill Notation) C12H13NO9

  • Molecular Weight 315.23

  •  Beilstein/REAXYS Number 1438576

  •  EC Number 233-753-0

  •  MDL number MFCD00036210

  •  PubChem Substance ID 24897507




4-Nitrophenyl β-D-glucuronide has been used as substrate in acetate buffer to measure β-glucuronidase.


1, 2 g in poly bottle

25, 50, 100, 250 mg in poly bottle


Chromogenic substrate for β-glucuronidase (GUS) gene detection.

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 


Certificate of Analysis


Certificate of Origin

Protocols & Articles


Drug Conjugate Analysis

Glucuronidation by the human UDPglucuronosyltransferase (UGT) family of enzymes plays an important role in the metabolic fate of many drugs and other xenobiotics. This biosynthetic reaction also has ...
Robert Gates
Biofiles Volume 6 Article 1
Keywords: Bacterial conjugations, Chromatography, Gas chromatography, High performance liquid chromatography, Immunoassay, Mass spectrometry, Metabolites

Fermentation: Enzymes, Substrates and SCFA

The influence of probiotics on the metabolic activity of intestinal microbiota may be evaulated by detecting bacterial enzymatic activity in fecal samples, specifically β-glucosidase, β-glucuronidase...
Chloe McClanahan
Biofiles Edition 6.2
Keywords: Absorption, Cancer, Carcinogens, Cell proliferation, Chromatography, Enzyme activity, Gas chromatography, Gastrointestinal, High performance liquid chromatography, Metabolites, Prebiotics, Probiotics, Thin layer chromatography

Probiotics and Human Health

At the beginning of the 20th century, probiotics were thought to have a beneficial effect to the host by improving the intestinal microbial balance. Through his studies and observations, the Russian ...
Chloe McClanahan
BioFiles Edition 6.2
Keywords: AGE, Absorption, Adhesion, Amplification, Anaerobic, Antimicrobials, Cancer, Carcinogens, Cell proliferation, Chromatography, Coagulation, Detoxification, Diagnostic, Diseases, Enzyme activity, Fermentation, Gas chromatography, Gastrointestinal, High performance liquid chromatography, Inflammation, Magnetic resonance spectroscopy, Metabolism, Metabolites, Molecular biology, Nucleic acid hybridization, PAGE, Pharmaceutical, Phosphorylations, Polymerase chain reaction, Prebiotics, Probiotics, Reductions, Respiratory, Sequencing, Thin layer chromatography, Titrations

Peer-Reviewed Papers


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