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N2162 Sigma-Aldrich

NH125

≥98% (HPLC), solid

Synonym: 1-Benzyl-3-cetyl-2-methylimidazolium iodide

  • CAS Number 278603-08-0

  • Empirical Formula (Hill Notation) C27H45IN2

  • Molecular Weight 524.56

  •  MDL number MFCD07370143

  •  PubChem Substance ID 329818598

  •  NACRES NA.77

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   100
assay   ≥98% (HPLC)
form   solid
color   white to off-white
mp   88.2-94.9 °C
solubility   DMSO: >20 mg/mL
storage temp.   −20°C
SMILES string   [I-].CCCCCCCCCCCCCCCC[n+]1ccn(Cc2ccccc2)c1C
InChI   1S/C27H45N2.HI/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-19-22-28-23-24-29(26(28)2)25-27-20-17-16-18-21-27;/h16-18,20-21,23-24H,3-15,19,22,25H2,1-2H3;1H/q+1;/p-1
InChI key   RVWOHCBHAGBLLT-UHFFFAOYSA-M

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

NH125 is a novel plant histidine kinase inhibitor and selective mammalian eurkaryotic elongation factor-2 kinase (eEF-2K).

Packaging

Packaged under nitrogen.

Analysis Note

IC50 = 60 nM for eEF-2 kinase vs protein kinase C (IC50= 7.5 μM), protein kinase A (IC50= 80 μM), and calmodulin-dependent kinase II IC50 > 100 μM).

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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