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N4415 Sigma-Aldrich

NGA2F Glycan

from Porcine

Synonym: (GlcNAc)2Man3(Fuc)(GlcNAc)2, Asialo, agalacto, biantennary N-glycan, core fucosylated, FA2 N-glycan, Mannotriose-(fucosyl-di-[N-acetylglucosamine]), bis(N-acetylglucosaminyl)-

  • CAS Number 84825-26-3

  • Empirical Formula (Hill Notation) C56H94N4O40

  • Molecular Weight 1463.35

  •  MDL number MFCD01310896

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Properties

biological source   Porcine
storage temp.   −20°C

Description

Biochem/physiol Actions

NGA2F N-glycan is a fucosylated biantennary oligosaccharide (FBO) that may be found in the Fc region of IgG. In a study of glycans isolated from a recombinant monoclonal IgG1, high-mannose oligosaccharides were reported to be cleared at a faster rate than FBOs. A study of diethylnitrosamine (DENA) induced hepatocellular carcinoma (HCC) in rats found significant elevation levels of two specific N-glycans compared to NGA2F N-glycan levels in HCC rats. NGA2F, NGA2FB, and NA2F N-glycan levels in normal human serum were found to be age- and gender-dependent.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
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