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N9876 Sigma-Aldrich

4-Nitrophenyl butyrate

≥98%

Synonym: p-Nitrophenyl butyrate, Butyric acid 4-nitrophenyl ester

  • CAS Number 2635-84-9

  • Empirical Formula (Hill Notation) C10H11NO4

  • Molecular Weight 209.20

  •  Beilstein/REAXYS Number 1879729

  •  MDL number MFCD00047734

  •  PubChem Substance ID 24897915

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Properties

Related Categories Biochemicals and Reagents, Chromogen, Enzyme Substrate, Fatty Acyls, Lipids More...
InChI Key   DVDUMIQZEUTAGK-UHFFFAOYSA-N
assay   ≥98%
density   1.19 g/mL at 20 °C (lit.)
storage temp.   −20°C

Description

General description

4-Nitrophenyl butyrate is a substrate for esterase, and lipase enzyme. Hydrolysis of 4-nitrophenyl butyrate by these enzymes releases the chromophore, 4-nitrophenolate which is spectrophotometrically analysed at 415 nm.

Application

4-nitrophenyl butyrate has been used:
• as a substrate for esterase activity in monocyte-derived macrophage cell line in response to polyethylene
• as a substrate for mycobacterial phospholipase A and mycobacterial cutinase activity
• as a substrate to determine the effect of buffers and solvents on human carboxylesterase

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Certificate of Origin

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Protocols & Articles
Peer-Reviewed Papers
15

References

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