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O1764 Sigma-Aldrich

N-(3-Oxooctanoyl)-L-homoserine lactone

≥97% (HPLC), white powder

Synonym: N-(β-Ketooctanoyl)-L-homoserine

  • CAS Number 147795-39-9

  • Empirical Formula (Hill Notation) C12H19NO4

  • Molecular Weight 241.28

  •  MDL number MFCD08277025

  •  eCl@ss 32160406

  •  PubChem Substance ID 24897950

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Gene Regulation and Expression, Microbiology, PPAR and RXR Regulators,
Quality Level   200
assay   ≥97% (HPLC)
form   white powder
solubility   chloroform: 50 mg/mL, clear, colorless
shipped in   wet ice
storage temp.   −20°C
SMILES string   CCCCCC(=O)CC(=O)N[C@H]1CCOC1=O
InChI   1S/C12H19NO4/c1-2-3-4-5-9(14)8-11(15)13-10-6-7-17-12(10)16/h10H,2-8H2,1H3,(H,13,15)/t10-/m0/s1
InChI key   FXCMGCFNLNFLSH-JTQLQIEISA-N

Description

General description

N-(3-Oxooctanoyl)-L-homoserine lactone is a common quorum sensing (QS) signal.

Application

N-(3-Oxooctanoyl)-L-homoserine lactone has been used to study the effects of pH, temperature and salinity on extracellular polymeric substances (EPS) of Pseudomonas aeruginosa biofilm.

Packaging

10, 100 mg in glass bottle

Biochem/physiol Actions

N-(3-Oxooctanoyl)-L-homoserine lactone stimulates the tra gene expression. It is an autoinducer and potent antagonist.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

Microbiology Introduction

An initial aim of all microbiologists is the reproducible growth of their microbial cultures, no matter whether the microorganisms are of natural origin or have been genetically engineered by man. Re...
Keywords: Absorption, Aerobic, Anaerobic, Antibiotics, Antimicrobials, Buffers, Culture media, Diffusion, Environmental, Filtration, Genetic, Growth factors, Metabolism, Phase transitions, Precipitation, Reductions, Respiration, Sample preparations, Vitamins

Peer-Reviewed Papers
15

References

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06693 Timestrip Plus -20 °C

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