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P0747 Sigma

8-MA-cAMP

≥98% (HPLC), solid

Synonym: 8-Methylaminoadenosine-3′,5′-cyclic monophosphate sodium salt

  • CAS Number 33823-18-6

  • Empirical Formula (Hill Notation) C11H14N6O6PNa

  • Molecular Weight 380.23

  •  MDL number MFCD04113731

  •  PubChem Substance ID 24724571

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, Protein Kinase A (PKA), Serine/Threonine Kinase Activators,
InChI Key   PYXGPPLPPUIPRE-MCDZGGTQSA-M
assay   ≥98% (HPLC)
form   solid
packaging   pkg of 10 μmol
color   white
solubility   H2O: freely soluble
shipped in   dry ice
storage temp.   −70°C

Description

Biochem/physiol Actions

Selective cAMP-dependent protein kinase (PKA) activator. Site selective cyclic AMP analogue with similar affinity to site B of both protein kinase A type I and II. Priming analogue which acts synergistically together with analogues showing site A preference. Together with e.g. 8-piperidino cAMP, selective stimulation of type I can be achieved.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

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