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P207 Sigma-Aldrich

Philanthotoxin 433 tris(trifluoroacetate) salt

≥98% (HPLC), powder

Synonym: (S)-N-[4-[[3-[(3-Aminopropyl)amino]propyl]amino]butyl]-4-hydroxy-α-[(1-oxobutyl)amino]benzenepropanamide tris(trifluoroacetate) salt, PhTX-433 tris(trifluoroacetate) salt

  • CAS Number 276684-27-6

  • Empirical Formula (Hill Notation) C23H41N5O3 · 3C2HF3O2

  • Molecular Weight 777.67

  •  MDL number MFCD00661076

  •  PubChem Substance ID 24898269

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Neurobiology, Neuroscience, Pharmacologicals,
assay   ≥98% (HPLC)
form   powder
storage condition   desiccated
color   white to beige
solubility   H2O: ≥10 mg/mL
storage temp.   −20°C
SMILES string   OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCCCCNCCCNCCCN
InChI   1S/C23H41N5O3.3C2HF3O2/c1-2-7-22(30)28-21(18-19-8-10-20(29)11-9-19)23(31)27-17-4-3-13-25-15-6-16-26-14-5-12-24;3*3-2(4,5)1(6)7/h8-11,21,25-26,29H,2-7,12-18,24H2,1H3,(H,27,31)(H,28,30);3*(H,6,7)/t21-;;;/m0.../s1
InChI key   UROZAUWUTBOQNV-YDULTXHLSA-N
Gene Information   human ... GRIN1(2902)
mouse ... GRIN1(14810)
rat ... GRIN1(24408)

Description

Biochem/physiol Actions

Philanthotoxin 433 is a polyamine-containing toxin, which blocks NMDA-gated ion channels; originally isolated from the venom of the wasp Philanthus triangulum.

Caution

hygroscopic

Reconstitution

Addition of 1 mL of solvent to vial yields a 1 mM solution.

Legal Information

Sold under license from Columbia University.

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
UN 2811 6.1 / PGII
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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