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P2508 Sigma-Aldrich

Proflavine hemisulfate salt hydrate

powder

Synonym: 3,6-Diaminoacridine hemisulfate salt

  • CAS Number 1811-28-5

  • Empirical Formula (Hill Notation) C13H11N3 · 0.5 H2SO4 · xH2O

  • Molecular Weight 258.29 (anhydrous basis)

  •  Beilstein/REAXYS Number 3921806

  •  EC Number 217-320-3

  •  MDL number MFCD00149650

  •  PubChem Substance ID 24898329

  •  NACRES NA.47

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Properties

Related Categories Biochemicals and Reagents, Cell Biology, Hematology and Histology, Luminescent Compounds/Detection, P,
Quality Level   100
form   powder
fluorescence   λex 444 nm; λem 508 nm (0.01M HCl)
SMILES string   [H]O[H].OS(O)(=O)=O.Nc1ccc2cc3ccc(N)cc3nc2c1.Nc4ccc5cc6ccc(N)cc6nc5c4
InChI   1S/2C13H11N3.H2O4S.H2O/c2*14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10;1-5(2,3)4;/h2*1-7H,14-15H2;(H2,1,2,3,4);1H2
InChI key   DTRLDKDFCPUGCA-UHFFFAOYSA-N

Description

General description

Proflavine is a small, amphipathic, acridine-derived fluorescent dye.Proflavine hemisulfate is used as a rapid stain for cytological studies of biological specimens. It stains cytoplasmic structures and nuclei. Proflavine has the capability to intercalate double stranded DNA.

Application

Proflavine hemisulfate salt hydrate has been used to stain cells of the 1483 cell line. It has also been used as a calibrating dye in fluorescence resonance energy transfer (FRET) analysis.

Packaging

1, 10, 25 g in glass bottle

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
AR9065100

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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