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P3657 Sigma-Aldrich

Pyridoxal 5′-phosphate hydrate

powder, BioReagent, suitable for cell culture

Synonym: 3-Hydroxy-2-methyl-5-([phosphonooxy]methyl)-4-pyridinecarboxaldehyde, Codecarboxylase, PLP, Pyridoxal 5-phosphate

  • CAS Number 853645-22-4

  • Empirical Formula (Hill Notation) C8H10NO6P · xH2O

  • Molecular Weight 247.14 (anhydrous basis)

  •  Beilstein/REAXYS Number 234749

  •  EC Number 200-208-3

  •  MDL number MFCD00006333

  •  PubChem Substance ID 24898438

  •  NACRES NA.75

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Properties

Related Categories Aldehydes, Biochemicals and Reagents, Building Blocks, C8, Carbonyl Compounds,
Quality Level   200
product line   BioReagent
assay   ≥98%
form   powder
mol wt   Mw 247.14 g/mol
application(s)   cell culture | mammalian: suitable
color   off-white to yellow-brown
mp   140-143 °C
solubility   1 M HCl: soluble 50 mg/mL, clear, colorless to light yellow-green
storage temp.   −20°C
SMILES string   CC1=NC=C(COP(O)(O)=O)C(C([H])=O)=C1O
InChI   1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)
InChI key   NGVDGCNFYWLIFO-UHFFFAOYSA-N

Description

General description

Pyridoxal-phosphate (PLP, pyridoxal-5′-phosphate, P5P) is a prosthetic group of some enzymes. It is the active form of vitamin B6, which comprises three natural organic compounds, pyridoxal, pyridoxamine and pyridoxine. PLP acts as a coenzyme in all transamination reactions, and in some decarboxylation and deamination reactions of amino acids.

Packaging

1 g in poly bottle

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

Insulin Signaling and Energy Homeostasis

Glucose metabolism is regulated by the opposing actions of insulin and glucagon. Insulin is released from pancreatic ß cells in response to high blood glucose levels and regulates glucose metabolism ...
Linda Stephenson, Ph.D.
Biofiles v6 n4, 2011
Keywords: Apoptosis, Biological processes, Carboxylations, Catalog, Diabetes, Gene expression, Gluconeogenesis, Glycolysis, Hormones, Metabolism, Metabolites, Transcription, Transduction, Type

Related Content

Vitamin B6, Pyridoxal and Pyridoxine, in Cell Culture

Importance and uses of the B6 vitamins, pyridoxal and pyridoxine, in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures
Keywords: Catalysis, Cell culture, Culture media, Decarboxylations, Degradations, Eliminations, Metabolism, Neurotransmitters, Racemizations, Transaminations, Vitamins

Peer-Reviewed Papers
15

References

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