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P5390 Sigma-Aldrich

Prostaglandin B2

≥98%, synthetic

Synonym: (5Z,13E,15S)-15-Hydroxy-9-oxoprosta-5,8(12),13-trien-1-oic acid, PGB2

  • CAS Number 13367-85-6

  • Empirical Formula (Hill Notation) C20H30O4

  • Molecular Weight 334.45

  •  Beilstein/REAXYS Number 2153006

  •  MDL number MFCD00065730

  •  PubChem Substance ID 24898630

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Properties

Related Categories Allium sativum (Garlic), Arachidonic Acid Cascade, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents,
biological source   synthetic
InChI Key   PRFXRIUZNKLRHM-HKVRTXJWSA-N
assay   ≥98%
form   solution
solubility   ethanol: ~100 mg/mL
  PBS, pH 7.2: ~2 mg/mL
  DMSO: ~50 mg/mL
storage temp.   −20°C

Description

Biochem/physiol Actions

Primary prostaglandin of osteoblasts; induces pulmonary hypertension.

Physical form

Prostaglandin B2 is supplied as a solution in methyl acetate

Preparation Note

PGB2 is provided as a solution in methyl acetate. To change the solvent, evaporate the methyl acetate under a gentle stream of nitrogen and immediately add the solvent of choice. PGB2, purged with an inert gas, is soluble in ethanol at ~100 mg/mL, DMSO at ~50 mg/mL and in dimethyl formamide at ~ 75 mg/mL.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Supplemental Hazard Statements 
Repeated exposure may cause skin dryness or cracking.
RIDADR 
UN1231 - class 3 - PG 2 - Methyl acetate, solution
WGK Germany 
2
Flash Point(F) 
15.8 °F
Flash Point(C) 
-9 °C

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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