• USA Home
  • P7794 - Penicillin G potassium salt

EMAIL THIS PAGE TO A FRIEND
P7794 Sigma-Aldrich

Penicillin G potassium salt

powder, BioReagent, suitable for cell culture

Synonym: Benzylpenicillin potassium salt

  • CAS Number 113-98-4

  • Empirical Formula (Hill Notation) C16H17KN2O4S

  • Molecular Weight 372.48

  •  Beilstein/REAXYS Number 3832841

  •  EC Number 204-038-0

  •  MDL number MFCD00036193

  •  eCl@ss 34010400

  •  PubChem Substance ID 24898878

Purchase

Properties

Related Categories Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics N-S, Antibiotics by Mechanism of Action,
InChI Key   IYNDLOXRXUOGIU-LQDWTQKMSA-M
product line   BioReagent
form   powder
potency   1440-1680 units per mg
shelf life   limited shelf life, expiry date on the label
application(s)   cell culture | mammalian: suitable
solubility   H2O: 100 mg/mL
suitability   suitable for cell culture
Mode of action   cell wall synthesis | interferes
antibiotic activity spectrum   Gram-positive bacteria

Description

General description

Chemical structure: ß-lactam

Application

Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. It is the drug of choice for groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridians group streptococci, and non-penicillinase producing staphylococcus. The potassium salt has been used to study murosomes of staphylococci and the penicillin-induced lysis of Streptococcus mutans.

Biochem/physiol Actions

Mode of Action: Penicillin G acts by inhibiting cell wall synthesis through binding to penicillin binding proteins (PBPs), inhibiting peptidoglycan chain cross-linking.

Antimicrobial spectrum: This product is active against gram-positive and gram-negative bacteria.

Caution

Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for more lengthy periods. Solutions are stable at 37°C for 3 days. The potassium salt is soluble in H2O at 100 mg/mL.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.Handle and store under inert gas. Keep in a dry place

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
XH9700000

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Certificate of Origin (COO)

Please Enter a Lot Number

Pipette Controller from Brand

Cell Culture Guide
Protocols & Articles

Related Content

Antibiotics Selection Guide

The Antibiotic Selection Guide enables researchers to spend more time on their research discoveries and less time seeking established antibiotic information. Link to hundreds of antibiotics for conta...
Keywords: Antibiotics, Cell biology, Cell culture, Genetic, High performance liquid chromatography, Reversed-phase chromatography

Cell Culture Troubleshooting Guide

Cell culture has become one of the most fundamental techniques for modeling biological systems, and is of increasing importance in the biotechnology and pharmaceutical sectors as well as an essential...
Keywords: Antibiotics, Apoptosis, Cell attachment, Cell culture, Cryopreservation, Filtration, Growth factors, Pharmaceutical, Phase transitions

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?