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P8296 Sigma-Aldrich

5-Phospho-D-ribose 1-diphosphate pentasodium salt

≥75% (HPLC)

Synonym: α-D-Ribosyl diphosphate 5-phosphate pentasodium salt, 5-Phospho-α-D-ribosyl diphosphate, 5-Phosphoribosyl 1-pyrophosphate pentasodium salt, P-Rib-PP, PRPP pentasodium salt

  • CAS Number 108321-05-7

  • Empirical Formula (Hill Notation) C5H8Na5O14P3

  • Molecular Weight 499.98

  •  Beilstein/REAXYS Number 6043637

  •  PubChem Substance ID 24898743

  •  NACRES NA.25

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Properties

Related Categories Carbohydrate, Cell Biology, Metabolic Pathways, Metabolites and Cofactors on the Metabolic Pathways Chart, Metabolomics More...
Quality Level   300
assay   ≥75% (HPLC)
form   powder
shipped in   dry ice
storage temp.   −20°C
SMILES string   [Na+].[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@H](O[C@@H]1COP(O)([O-])=O)OP([O-])(=O)OP([O-])([O-])=O

Description

Application

Pentasodium salt has been used in a study to assess the relationship between the muscarinic receptor cationic current and internal calcium in guinea-pig jejunal smooth muscle cells. It has also been used in a study to investigate inhibitors of the bacterial cell wall biosynthesis of the enzyme Mur D.

Packaging

25, 100, 250, 500 mg in poly bottle

Substrates

Substrate for phosphoribosyltransferases in the synthesis of nucleotides.

Analysis Note

Purity ≥ 75% based on an assay system using orotidine-5′-phosphate pyrophosphorylase and orotidine-5′-phosphate decarboxylase mixed enzymes.

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Nucleotide Synthesis in Cancer Cells

Neoplastic cells are highly dependent on the de novo synthesis of nucleotides to maintain sufficient pools to support DNA replication and the production of RNA. The metabolic pathways supporting nucl...
BioFiles v7 n4
Keywords: Cancer, Catalysis, Citric Acid Cycle, DNA replication, Gene expression, Glycolysis, Metabolic Pathways, Metabolism, Metabolites, Nucleotide Synthesis, Pentose phosphate pathway, Pyrimidine synthesis

Peer-Reviewed Papers
15

References

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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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