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PLA0031 Sigma-Aldrich

Rabbit anti-TRX2 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym: Rabbit anti-TRX2 Antibody, Affinity Purified



Related Categories Antibodies, Antibodies for Proximity Ligation Assays, Individual Antibodies More...
species reactivity   human, primate, gorilla, chimpanzee, rhesus monkey, gibbon
application(s)   ChIP: 1- 5 μg
  immunoprecipitation (IP): 5- 10 μg/mg
  proximity ligation assay: 1:1,000-1:10,000
  western blot: 1:500- 1:5,000
concentration   1 mg/mL
antibody form   affinity purified immunoglobulin
grade   Powered by Bethyl Laboratories, Inc.
shipped in   wet ice
storage temp.   2-8°C
Gene Information   rabbit ... TRX2(9757)
biological source   rabbit
antibody product type   primary antibodies
accession no.   NP_055542.1



The epitope recognized by PLA0031 maps to a region between residue 2375 and 2425 of human Trithorax 2 using the numbering given in entry NP_055542.1 (GeneID 9757).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide


Product PLA0031, Powered by Bethyl Laboratories, has been pre-qualified for use in proximity ligation assay (PLA®). PLA® technology enables visualization of protein interactions in fixed cells and tissue samples while under endogenous protein expression levels.

Other Notes

Human trithorax homolog 2 (TRX2) is a member of the MLL sub-family of proteins that are found in Set1-like histone H3 K4 methyltransferase complexes. TRX2 may function as a transactivator that mediates cell adhesion and cytoskeletal events important to cell growth and survival. TRX2 is also known as MLL2. The MLL2 complex includes MLL2 (TRX2), ASH2, RBQ3, WDR5, hDPY-30, and menin. MLL2 has been shown to interact with ER-alpha to regulate estrogen-induced gene expression and has been implicated in tumorigenesis.

Legal Information

PLA is a registered trademark of Sigma-Aldrich Co. LLC


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety & Documentation

Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  nwg
Protocols & Articles


Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

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