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PZ0274 Sigma

PF-01247324

≥98% (HPLC)

Synonym: 6-Amino-5-(2,3,5-trichlorophenyl)pyridine-2-carboxylic acid methylamide, 6-Amino-N-methyl-5-(2,3,5-trichlorophenyl)-2-Pyridinecarboxamide, N-Methyl-6-amino-5-(2,3,5-trichlorophenyl)pyridine-2-carboxamide, PF 01247324, PF-1247324

  • CAS Number 875051-72-2

  • Empirical Formula (Hill Notation) C13H10Cl3N3O

  • Molecular Weight 330.60

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Ion Channels,
assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   DMSO: 20 mg/mL, clear
originator   Pfizer
storage temp.   room temp

Description

Other Notes

This compound was developed by Pfizer for Ion Channel research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Packaging

5, 25 mg in glass bottle

Legal Information

Sold for research purposes under agreement from Pfizer Inc.

Biochem/physiol Actions

PF-01247324 is an orally bioavailable, selective and potent NaV1.8 channel blocker that inhibits that exhibits analgesic efficacy in rodent behavioral models of pain.

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles

Articles

Discover Bioactive Small Molecules for Ion Channels Research

Ion transport across the relatively impermeable lipid bilayer of the cell membrane is accomplished via membrane proteins known as ion channels, pumps and transporters. Ion channels are gated pores an...
Keywords: Biological processes, Cell signaling, Diseases, Hormones, Ligands, Neurotransmitters

Pfizer Compounds for Ion Channels

From our library of Articles, Sigma-Aldrich presents Pfizer Compounds for Ion Channels

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