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PZ0343 Sigma-Aldrich

PF-06260414

≥98% (HPLC)

Synonym: 6-[(4R)-tetrahydro-4-methyl-1,1-dioxido-2H-1,2,6-thiadiazin-2-yl]-1-isoquinolinecarbonitrile

  • CAS Number 1612755-71-1

  • Empirical Formula (Hill Notation) C14H14N4O2S

  • Molecular Weight 302.35

  •  PubChem Substance ID 329823852

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Properties

Related Categories Androgen, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
mfr. no.   Pfizer®
color   light orange to dark orange
solubility   DMSO: 5 mg/mL, clear (warmed)
originator   Pfizer
storage temp.   room temp
SMILES string   C[C@H](CNS1(=O)=O)CN1C2=CC3=CC=NC(C#N)=C3C=C2
InChI   1S/C14H14N4O2S/c1-10-8-17-21(19,20)18(9-10)12-2-3-13-11(6-12)4-5-16-14(13)7-15/h2-6,10,17H,8-9H2,1H3/t10-/m1/s1
InChI key   ZKAVFOXYJCREBQ-SNVBAGLBSA-N

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

PF-06260414 is a nonsteriodal selective androgen receptor modulator (SARM). PF-06260414 is being investigated as a treatment for muscle weakening such as that associated with muscular dystrophy and the sarcopenia associated with natural aging. PF-06260414 has anabolic activity without unwanted androgenic activity on reproductive organs, liver or kidneys.

Other Notes

This compound was developed by Pfizer for Cytokines & Growth Factors research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

Legal Information

Sold for research purposes under agreement from Pfizer Inc.

Pfizer is a registered trademark of Pfizer, Inc.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Pfizer Compounds for Cytokines and Growth Factors

From our library of Articles, Sigma-Aldrich presents Pfizer Compounds for Cytokines and Growth Factors

Peer-Reviewed Papers
15

References

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