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PZ0387 Sigma-Aldrich

PF-562,271

≥98% (HPLC)

Synonym: N-(3-(((2-((2,3-Dihydro-2-oxo-1H-indol-5-yl)amino)-5- (trifluoromethyl)-4-pyrimidinyl)amino)methyl)-2-pyridinyl)-N-methyl-methanesulfonamide benzenesulfonate, PF 562271, PF-00562271, PF-562271

  • CAS Number 939791-38-5

  • Empirical Formula (Hill Notation) C21H20F3N7O3S · C6H6O3S

  • Molecular Weight 665.66

  •  MDL number MFCD14105612

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, P-PH
assay   ≥98% (HPLC)
form   powder
color   white to brown
solubility   DMSO: 2 mg/mL, clear
storage temp.   2-8°C

Description

Legal Information

Sold for research purposes under agreement from Pfizer Inc.

Biochem/physiol Actions

PF-562,271 is a potent, ATP-competitive, reversible and selective inhibitor of FAK and Pyk2. PF-562,271 inhibits FAK phosphorylation in vivo.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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