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R140 Sigma-Aldrich

Ro 04-6790 dihydrochloride

solid

Synonym: 4-Amino-N-[2,6-bis(methylamino)-4-pyrimidinyl]benzenesulfonamide dihydrobromide

  • CAS Number 202466-68-0

  • Empirical Formula (Hill Notation) C12H16N6O2S · 2HCl

  • Molecular Weight 381.28

  •  MDL number MFCD11045584

  •  PubChem Substance ID 24278570

  •  NACRES NA.77

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Properties

Related Categories Antagonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents,
form   solid
color   white
solubility   DMSO: >10 mg/mL
  H2O: >10 mg/mL
originator   Roche
SMILES string   Cl.Cl.CNc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(NC)n1
InChI   1S/C12H16N6O2S.2ClH/c1-14-10-7-11(17-12(15-2)16-10)18-21(19,20)9-5-3-8(13)4-6-9;;/h3-7H,13H2,1-2H3,(H3,14,15,16,17,18);2*1H
InChI key   QOAXXMSJHQHSFV-UHFFFAOYSA-N
Gene Information   human ... HTR6(3362)

Description

Packaging

25 mg in poly bottle

5 mg in glass bottle

Biochem/physiol Actions

Selective 5-HT6 serotonin receptor antagonist.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Caution

Photosensitive

Legal Information

Manufactured and sold under license from Hoffman LaRoche.

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
DA9462500

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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