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R8782 Sigma-Aldrich

Ro4368554

≥98% (HPLC)

Synonym: 3-benzenesulfonyl-7-(4-methyl-piperazin-1-yl)-1H-indole, 7-(4-methyl-1-piperazinyl)-3-(phenylsulfonyl)-1H-Indole

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Properties

Related Categories Antagonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology,
InChI Key   AOPYPEADLGTXRA-UHFFFAOYSA-N
assay   ≥98% (HPLC)
form   powder
color   off-white
solubility   DMSO: >10 mg/mL
originator   Roche
storage temp.   room temp

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

Ro4368554 is a 5-HT6 receptor antagonist. RO4368554 acts selectively at 5-HT6 receptors where it binds with a greater than 100-fold selectivity over other monoamine receptor subtypes (-log M pKi = 9.4 at 5-HT6 and 7.1 at 5-HT2A).

Features and Benefits

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
2

Documents

Certificate of Analysis

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Making Headway

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Protocols & Articles

Articles

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