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S0508 Sigma-Aldrich

Sulfamonomethoxine

Synonym: 4-Methoxy-6-sulfanilamidopyrimidine, 4-Amino-N-(6-methoxy-4-pyrimidinyl)benzenesulfonamide, N1-(6-Methoxy-4-pyrimidinyl)sulfanilamide, SMM

  • CAS Number 1220-83-3

  • Empirical Formula (Hill Notation) C11H12N4O3S

  • Molecular Weight 280.30

  •  Beilstein/REAXYS Number 621128

  •  MDL number MFCD00063466

  •  PubChem Substance ID 24899439

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Properties

Related Categories Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics N-S, Antibiotics by Mechanism of Action,
InChI Key   WMPXPUYPYQKQCX-UHFFFAOYSA-N
form   powder
color   white to yellow-white
solubility   methanol: soluble 10 mg/mL
Mode of action   DNA synthesis | interferes
  enzyme | inhibits
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria
  parasites

Description

General description

Chemical structure: sulfonamide

Application

Sulfamonomethoxine is a long acting sulfonamide antibacterial agent. It is used to study degradation by Fe3O4 magnetic nanoparticles. It is used in blood kinetic studies and is used to study capsule formation of Bordetella bronchiseptica.

Packaging

1 g in glass bottle

250 mg in glass bottle

Biochem/physiol Actions

Sulfamonomethoxine is a competitive inhibitor of dihydropteroate synthetase used to block the synthesis of folic acid.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
WP0550000

Documents

Certificate of Analysis

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Protocols & Articles
Peer-Reviewed Papers
15

References

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