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S3313 Sigma-Aldrich

SB-204070 hydrochloride

solid, ≥97% (HPLC)

Synonym: (1-Butyl-4-piperidinyl)methyl-8-amino-7-chloro-1,4-benzodioxane-5-carboxylate hydrochloride

  • CAS Number 148702-58-3

  • Empirical Formula (Hill Notation) C19H27ClN2O4 · HCl

  • Molecular Weight 419.34

  •  MDL number MFCD03453014

  •  PubChem Substance ID 24278704

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Description

Application

SB-204070 hydrochloride was used to study the role of 5-HT metabolites in trypsin-induced anion secretion in mouse cecum.

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

SB-204070 is a highly potent and specific antagonist of 4-HT4 receptor. It inhibits cholinergic and noncholinergic transmission and blocks the contractions of proximal colon in guinea pigs and relaxation of human colon circular smooth muscle.

Selective 5-HT4 serotonin receptor antagonist.

Legal Information

Manufactured and sold under exclusive license from GlaxoSmithKline Pharmaceuticals

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Making Headway

Milli-Q® Water Purification Solutions
Protocols & Articles
Peer-Reviewed Papers
15

References

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