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S4500 Sigma

L-Serine

ReagentPlus®, ≥99% (HPLC)

Synonym: (S)-2-Amino-3-hydroxypropionic acid

  • CAS Number 56-45-1

  • Linear Formula HOCH2CH(NH2)CO2H

  • Molecular Weight 105.09

  •  Beilstein Registry Number 1721404

  •  EC Number 200-274-3

  •  MDL number MFCD00064224

  •  eCl@ss 32160406

  •  PubChem Substance ID 24899605

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Description

Biochem/physiol Actions

Precursor of glycine by serine hydroxymethyltransferase.

L-Serine is a non-essential amino acid that acts as a precursor for nucleotide synthesis. It has roles in the development and function of the central nervous system. L-Serine also has a role in cellular proliferation.

Packaging

1 kg in poly bottle

1, 100 g in poly bottle

Application

L-Serine has been used in the preparation of Tris-BSAN buffer for homogenization. It has also been used for quantitative analysis of excretion of polypeptides in normal urine.

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1

Stabilizer Protein and RNA Stabilization Reagents
Protocols & Articles

Articles

HPLC Analysis of FMOC-Serine Enantiomers on Astec® (R,R) P-CAP™

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of FMOC-Serine Enantiomers on Astec® (R,R) P-CAP™
Keywords: Chromatography, High performance liquid chromatography

Nucleotide Synthesis in Cancer Cells

Neoplastic cells are highly dependent on the de novo synthesis of nucleotides to maintain sufficient pools to support DNA replication and the production of RNA. The metabolic pathways supporting nucl...
Keywords: Biofiles, Cancer, Catalysis, Citric Acid Cycle, DNA replication, Gene expression, Glycolysis, Metabolic Pathways, Metabolism, Metabolites, Nucleotide Synthesis, PAGE, Pentose phosphate pathway, Pyrimidine synthesis, Support

Peer-Reviewed Papers
15

References

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